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  3. 「【論文成果報告】2025年~2026年」
  • 2026.06.01

    【論文成果報告】2025年~2026年

    田所 剛志 先生

    Albumin-Butyrylcholinesterase as a Novel Prognostic Biomarker for Hepatocellular Carcinoma Post-hepatectomy: A Retrospective Cohort Study with the Hiroshima Surgical Study Group of Clinical Oncology.

    Tadokoro T, Kobayashi T, Honmyo N, Kuroda S, Ohira M, Hashimoto M, Oishi K, Oshita A, Abe T, Onoe T, Kohashi T, Ohdan H.

    Annals of Surgical Oncology.32,1973–1984 (2025).
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    難波 洋介 先生

    Effect of abdominal aortic calcification on long-term outcomes after the first liver resection in very old patients with hepatocellular carcinoma

    Namba Y, Ohira M, Imaoka Y, Hamaoka M, Hashimoto M, Onoe T, Takei D, Oishi K, Yamaguchi M, Abe T, Tadokoro T, Fukuhara S, Oshita K, Matsubara K, Honmyo N, Kuroda S, Tahara H, Kobayashi T, Ide K, Ohdan H.

    Annals of Gastroenterological Surgery.2025;9:169–177.
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    別木 智昭 先生

    The steatosis-associated fibrosis estimator score is a useful indicator of recurrence and survival after initial curative hepatectomy for hepatocellular carcinoma

    Bekki T, Ohira M, Imaoka Y, Hattori M, Nakano R, Sakai H, Kuroda S, Tahara H, Ide K, Kobayashi T, Ohdan H.

    Annals of Gastroenterological Surgery.2025;9:178–187.
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    志田原 幸稔 先生

    Curative resection of multiple primary neuroendocrine tumors enabled by preoperative imaging: a case report

    Shidahara H, Hashimoto M, Mori K, Kuroda S, Tahara H, Kobayashi T, Ohdan H.

    Journal of Surgical Case Reports,2025,1,rjae805.

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    黒田 慎太郎 先生

    Questionnaire on the surgical indications for intrahepatic cholangiocarcinoma administered to Japanese board-certified expert hepatobiliary and pancreatic surgeons and instructors

    Kuroda S, Kobayashi T, Hatano E, Kubo S, Endo I, Ohdan H; JSHBPS2024‐ICC survey consortium.

    Journal of Hepato-Biliary-Pancreatic Sciences.2025;32:179–193.
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    大平 真裕 先生

    A phase I/II study of adoptive immunotherapy using donor liver graft-derived NK cell-enriched immune cells to prevent severe infection after liver transplantation

    Ohira M, Imaoka Y, Sato K, Imaoka K, Bekki T, Yano T, Nakano R, Sakai H, Kuroda S, Tahara H, Ide K, Kobayashi T, Tanaka Y, Tanaka J, Ohdan H.

    PLoS One.2025 Jan 16;20(1):e0313102.
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    三枝 義尚 先生

    Cluster analysis of hepatocellular carcinoma prognosis using preoperative alpha-fetoprotein and des-gamma-carboxy prothrombin levels: a multi-institutional study

    Saegusa Y, Imaoka Y, Ohira M, Kobayashi T, Honmyo N, Hamaoka M, Onoe T, Takei D, Oishi K, Abe T, Nakayama T, Akabane M, Sasaki K, Ohdan H; Hiroshima Surgical Study Group of Clinical Oncology.

    J Gastrointest Surg. 2025 Apr;29(4):101980.
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    中村 真由奈 先生

    Antitumor effects of natural killer cells derived from gene-engineered human-induced pluripotent stem cells on hepatocellular carcinoma

    Nakamura M, Tanaka Y, Hakoda K, Ohira M, Kobayashi T, Kurachi K, Tamura K, Ohdan H.

    Cancer Immunology, Immunotherapy.74, 99 (2025).
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    荒田 了輔 先生

    Discrimination of Anti-Donor Response in Allogeneic Transplantation Using an Alloreactive T-Cell Detection Assay

    Arata R, Tanimine N, Seidakhmetov A, Ide K, Tanaka Y, Ohdan H.

    Transplant International.38:13879.
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    今岡 洸輝 先生

    Multivisceral resection as a key indicator of recurrence in locally advanced colorectal cancers with pathologic T3 tumors

    Imaoka K, Shimomura M, Okuda H, Yano T, Shimizu W, Yoshimitsu M, Ikeda S, Nakahara M, Kohyama M, Kobayashi H, Shimizu Y, Kochi M, Sumitani D, Mukai S, Takakura Y, Ishizaki Y, Kodama S, Fujimori M, Ishikawa S, Adachi T, Ohdan H.

    Journal of Gastrointestinal Surgery.2025 May;29(5):102015.
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    今岡 洸輝 先生

    Intraoperative Blood Loss Predicts Local Recurrence After Curative Resection for Stage I-III Colorectal Cancer

    Imaoka K, Shimomura M, Okuda H, Yano T, Shimizu W, Yoshimitsu M, Ikeda S, Nakahara M, Kohyama M, Kobayashi H, Shimizu Y, Kochi M, Akabane S, Sumitani D, Mukai S, Takakura Y, Ishizaki Y, Kodama S, Fujimori M, Ishikawa S, Adachi T, Hattori M, Ohdan H.

    World Journal of Surgery.2025 May;49(5):1172-1182.
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    篠原 充 先生

    Recurrent Liver Abscess Caused by Mucoid-Type Klebsiella pneumoniae Successfully Treated With Hepatic Artery Antibiotic Infusion Therapy: A Case Report

    Shinohara M, Nakano R, Honmyo N, Sakai H, Shimizu S, Kuroda S, Tahara H, Ohira M, Ide K, Chosa K, Awai K, Kobayashi T, Ohdan H.

    Cureus 17(2): e79451.
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    築山 尚史 先生

    Impacts of high mobility group box protein 1 gene polymorphisms on morbidity and mortality after living donor liver transplantation

    Tsukiyama N, Tanaka Y, Yamane H, Tanimine N, Kuroda S, Tahara H, Ohira M, Ide K, Kobayashi T, Ohdan H.

    Transplant Immunology.2025 May;90:102225.
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    別木 智昭 先生

    C-reactive Protein-albumin-lymphocyte Index Is a Useful Indicator for Recurrence and Survival Following Curative Resection of Stage I-III Colorectal Cancer

    Bekki T, Shimomura M, Yano T, Watanabe A, Ishikawa S, Imaoka K, Ono K, Matsubara K, Mochizuki T, Hattori M, Akabane S, Ohdan H.

    Journal of the Anus, Rectum and Colon.2025 Apr 25;9(2):192-201.
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    難波 洋介 先生

    Usefulness of preoperative peripheral blood GPC3-positive circulating tumor cells in subclassification of Barcelona Clinic Liver Cancer stage B hepatocellular carcinoma: a retrospective cohort study

    Namba Y, Kobayashi T, Hirata Y, Tadokoro T, Fukuhara S, Oshita K, Honmyo N, Nakano R, Sakai H, Shimizu S, Kuroda S, Tahara H, Ohira M, Ide K, Tanaka Y, Ohdan H.

    Hepatology Research.2025;55(8):1172–83.
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    唐口 望実 先生

    Decline in the surgical workforce in urban and rural Japan and the regional quota system as a potential solution to surgeon shortages

    Karakuchi N, Matsumoto M, Saeki Y, Tanabe K, Ohdan H.

    Surgery Today.55,1810–1819 (2025).
    DOI ↗

    下村 学 先生

    Late anastomotic complication after laparoscopic surgery for clinical stage I low rectal cancers located within 5 cm of the anal verge: Sub-analysis of the ultimate trial

    Shimomura M, Yoshimitsu M, Tsukada Y, Ohdan H, Watanabe J, Fukunaga Y, Hirano Y, Sakamoto K, Hamamoto H, Horie H, Matsuhashi N, Kuriu Y, Nagai S, Hamada M, Yoshioka S, Ohnuma S, Hayama T, Otsuka K, Inoue Y, Ueda K, Toiyama Y, Maruyama S, Yamaguchi S, Tanaka K, Suzuki M, Misumi T, Naitoh T, Watanabe M, Ito M; Ultimate Trial Group.

    Annals of Gastroenterological Surgery.2025;9:719–729.
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    三枝 義尚 先生

    Outcomes of Liver Transplantation Among Patients Diagnosed With Acute-on-Chronic Liver Failure: A Single-Center Experience

    Saegusa Y, Ohira M, Honmyo N, Nakano R, Sakai H, Shimizu S, Kuroda S, Tahara H, Ide K, Kobayashi T, Tanaka Y, Ohdan H.

    Transplantation Proceedings. 2025 Oct;57(8):1568-1573.
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    北村 芳仁 先生

    Durvalumab induced immune-related agranulocytosis after conversion surgery in a patient with intrahepatic cholangiocarcinoma: a case report

    Kitamura Y, Shimizu S, Kuroda S, Honmyo N, Nakano R, Sakai H, Tahara H, Ohira M, Ide K, Kobayashi T, Ichinohe T, Ohdan H.

    Frontiers in Immunology.16:1610190.
    DOI ↗

    大下 航 先生

    Prognostic Impact of C-reactive Protein-Albumin-Lymphocyte Index in Patients Who Underwent Splenectomy and Devascularization for Gastric Varices Caused by Portal Hypertension

    Oshita K, Kobayashi T, Honmyo N, Shimizu S, Kuroda S, Tahara H, Ohira M, Ide K, Ohdan H.

    Cureus. 2025 Jul 1;17(7):e87092.
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    山口 真治 先生

    Successful Treatment of Median Arcuate Ligament Syndrome in the Hybrid Operating Room: A Report of Four Cases

    Yamaguchi S, Nakano R, Honmyo N, Sakai H, Kuroda S, Tahara H, Ohira M, Ide K, Chosa K, Awai K, Kobayashi T, Ohdan H.

    Cureus. 2025 Jul 11;17(7):e87713.
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    篠原 充 先生

    Cases of Surgical Site Infection-Related Wound Dehiscence Treated with Negative Pressure Wound Therapy with Instillation and Dwell Time and Dialkylcarbamoyl Chloride

    Shinohara M, Yano T, Shimomura M, Okuda H, Akabane S, Mochizuki T, Oyama H, Ohdan H.

    Surgical Case Reports.2025;11(1):25-0241.
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    今岡 祐輝 先生

    FIB-3 index as a novel age-independent predictor of liver fibrosis and prognosis in hepatocellular carcinoma patients undergoing hepatectomy

    Imaoka Y, Ohira M, Kobayashi T, Honmyo N, Hamaoka M, Onoe T, Takei D, Oishi K, Abe T, Nakayama T, Akabane M, Sasaki K, Ohdan H; Hiroshima Surgical study group of Clinical Oncology (HiSCO).

    Annals of Gastroenterological Surgery.2025;9:1055–1065.
    DOI ↗

    Akhmet Seidakhmetov 先生

    Impact of SIRPα genotype combinations in recipients and donors on alloimmune response in liver transplantation

    Seidakhmetov A, Tanimine N, Tanaka Y, Arata R, Nakano R, Sakai H, Ohira M, Tahara H, Ide K, Kobayashi T, Ohdan H.

    PNAS Nexus. 2025 Nov 5;4(11):pgaf351.
    DOI ↗

    竹井 大祐 先生

    Clinical Significance of Circulating Tumor Cells in the Portal Vein of Patients with Hepatocellular Carcinoma Undergoing Anatomical Liver Resection

    Takei D, Kobayashi T, Hamaoka M, Matsubara K, Oshita K, Namba Y, Tadokoro T, Tanaka Y, Kuroda S, Ohdan H.

    Annals of Surgical Oncology. 2025 Dec;32(13):9561-9572.
    DOI ↗

    高畑 明寛 先生

    Impact of Abdominal Aortic Calcification on Long-Term Outcome after Gastric Cancer Surgery: a Retrospective Study

    Kohata A, Tanabe K, Shidahara H, Kohata S, Karakuchi N, Takemoto Y, Chikuie E, Ota H, Saeki Y, Ohdan H.

    Journal of Gastrointestinal Cancer, 56, 221 (2025).
    DOI ↗

    大下 航 先生

    Risk factors of conversion to hand-assisted laparoscopic surgery or open surgery in laparoscopic liver resection: a multicenter prospective study (HiSCO-08)

    Oshita K, Hamaoka M, Kobayashi T, Onoe T, Abe T, Kohashi T, Oishi K, Takei D, Akita T, Ohdan H. , Matsumoto M, Saeki Y, Tanabe K, Ohdan H.

    Sci Rep 16, 3873 (2026).
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    井手 健太郎 先生

    Time-unrestricted, Immune Surveillance-Guided Desensitization Enables Kidney Transplantation in Highly Sensitized Patients

    Ide K, Tahara H, Nakano R, Sakai H, Shimizu S, Ohira M, Tanaka Y, Ohdan H.

    Kidney International Reports.2025 Nov 4;11(1):233-236.
    DOI ↗

    今岡 洸輝 先生

    Intestinal obstruction impairs the antitumor function of hepatic natural killer cells against colorectal cancer

    Imaoka K, Ohira M, Yano T, Bekki T, Imaoka Y, Nakano R, Shimizu S, Shimomura M, Tanaka Y, Kobayashi T, Ohdan H.

    Journal of Gastroenterology 61, 450–461 (2026).
    DOI ↗

    下村 学 先生

    Possible preventive effect of surgical glove compression therapy on oxaliplatin-induced peripheral neuropathy: study protocol of a multicentre, phase II/III, randomised controlled trial-the Hiroshima Surgical Study Group of Clinical Oncology (HiSCO)-12 trial

    Shimomura M, Ishikawa S, Miguchi M, Shinozaki K, Ikeda S, Kobayashi H, Nakahara M, Sumitani D, Shimizu W, Kohyama M, Saito Y, Mukai S, Hirata Y, Kochi M, Shimizu Y, Takakura Y, Yoshimitsu M, Kodama S, Uegami S, Yano T, Okuda H, Ohdan H; Hiroshima Surgical study group of Clinical Oncology (HiSCO).

    BMJ Open 2026;16:e110878.
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    山口 瑞生 先生

    Thrombomodulin Mitigates the Progression of Hepatocellular Carcinoma in Steatotic Liver

    Yamaguchi M, Tashiro H, Kuroda S, Kobayashi T, Hinoi T, Honda G, Ohdan H.

    Journal of Hepatocellular Carcinoma.2026;13:568564.
    DOI ↗

    別木 智昭 先生

    Impact of Aspirin on Recurrence Prevention After Curative Resection for Stage I-III Colorectal Cancer: A Multi-Institutional Retrospective Study

    Bekki T, Shimomura M, Yano T, Imaoka K, Miguchi M, Sawada H, Hara T, Ono K, Kobayashi H, Sumi Y, Sada H, Sumitani D, Mukai S, Takakura Y, Yamaguchi M, Shiozaki S, Fujimori M, Taguchi K, Okuda H, Adachi T, Ishikawa S, Ohdan H; Hiroshima Surgical study group of Clinical Oncology (HiSCO).

    J Surg Oncol. 2026 May;133(6):720-729.
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    望月 哲矢 先生

    The dual role of peritoneal cavity B cells in the activation of antitumor T cells

    Mochizuki T, Tanaka Y, Ide R, Ohdan H.

    The Journal of Immunology, Volume 215, Issue 4, April 2026, vkag058.
    DOI ↗

    別木 智昭 先生

    Metformin enhances TRAIL-mediated antitumor activity of liver natural killer cells in mice

    Bekki T, Ohira M, Imaoka Y, Imaoka K, Niitsu H, Tanaka Y, Kobayashi T, Ohdan H.

    scientific reports 16, 18261 (2026).
    DOI ↗

    松原 啓壮 先生

    Identifying High-risk Patients with Synchronous Colorectal Liver Metastasis: Implications for Preoperative Chemotherapy Selection

    Matsubara K, Kobayashi T, Hashimoto M, Onoe T, Honmyo N, Mashima H, Yamaguchi M, Abe T, Hattori M, Ohdan H.

    Journal of the Anus, Rectum and Colon 2026 Apr 25;10(2):239-252.
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    別木 智昭 先生

    Serum Bile Acids Are Useful Indicators of Intrahepatic Recurrence After Initial Curative Hepatectomy for Hepatocellular Carcinoma

    Bekki T, Ohira M, Imaoka Y, Simizu S, Abe T, Kuroda S, Tahara H, Ide K, Kobayashi T, Ohdan H.

    Annals of Gastroenterological Surgery 2025 Dec 1;10(3):792-802.
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    田口 和浩 先生

    Perioperative and Oncological Outcomes of Colorectal Cancer Surgery in Obese Patients: A Multicenter Retrospective Study.

    Taguchi K, Shimomura M, Shimizu W, Ikeda S, Yoshimitsu M, Kouyama M, Nakahara M, Kobayashi H, Kochi M, Shimizu Y, Sumitani D, Mukai S, Takakura Y, Ishizaki Y, Kodama S, Fujimori M, Okuda H, Yano T, Bekki T, Watanabe A, Sato S, Moriuchi T, Shiozaki S, Matsubara K, Yamaguchi M, Adachi T, Ishikawa S, Ohdan H.

    Annals of Gastroenterological Surgery 2025 Dec 19;10(3):748-759.
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